Transplants provide better outcomes than dialysis for end-stage kidney disease

Transplants provide better outcomes than dialysis for end-stage kidney disease

December 18, 2018 — New data from the Canadian Institute for Health Information (CIHI) highlights the significant difference between dialysis and transplant outcomes for those being treated for end-stage kidney disease (ESKD). A focused look at 10-year outcome data shows that 16% of Canadians on dialysis survive past 10 years, whereas up to 74% of Canadians […]

Consistent success in life-supporting porcine cardiac xenotransplantation

Consistent success in life-supporting porcine cardiac xenotransplantation

Heart transplantation is the only cure for patients with terminal cardiac failure, but the supply of allogeneic donor organs falls far short of the clinical need1,2,3. Xenotransplantation of genetically modified pig hearts has been discussed as a potential alternative4. Genetically multi-modified pig hearts that lack galactose-α1,3-galactose epitopes (α1,3-galactosyltransferase knockout) and express a human membrane cofactor […]

Portable and Implantable Artificial Kidneys: AWAK, WAK, and IAK, oh my!

Portable and Implantable Artificial Kidneys: AWAK, WAK, and IAK, oh my!

Kidney disease carries a high burden for individual patients and for the medical system as a whole. End-stage kidney disease (ESKD) is associated with high mortality and decreased quality of life for many reasons including residual symptoms, pill burden, dietary restrictions, and decreased fertility. Kidney transplantation has benefits but is a limited resource, and the […]