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Improving the Supply and Quality of Deceased-Donor Organs for Transplantation

Solid-organ transplantation is the treatment of choice for many patients with end-stage diseases, but the supply of organs is limited. Recent advances are improving the quality and supply of organs for transplantation. Disclosure forms provided by the authors are available with the full text of this article at NEJM.org. We thank Drs. Sanjeev Noel and Timm…

The promise of organ and tissue preservation to transform medicine

The ability to replace organs and tissues on demand could save or improve millions of lives each year globally and create public health benefits on par with curing cancer. Unmet needs for organ and tissue preservation place enormous logistical limitations on transplantation, regenerative medicine, drug discovery, and a variety of rapidly advancing areas spanning biomedicine….

NIH clinical trial to track outcomes of kidney transplantation from HIV-positive donors to HIV-positive recipients

Two HIV awareness ribbons.NIAID The first large-scale clinical trial to study kidney transplantations between people with HIV has begun at clinical centers across the United States. The HOPE in Action Multicenter Kidney Study will determine the safety of this practice by evaluating kidney recipients for potential transplant-related and HIV-related complications following surgery. The study is…

El Dr. Cavadas reimplanta una mano después de 10 horas amputada del cuerpo

Submarino del ejército norteamericano, y en plenas maniobras, un marine sufre un accidente grave. Un accidente industrial catastrófico, El marine pierde su mano, queda amputada completamente. Empieza el rescate. Todo pinta mal. Pero, dentro de lo malo, este accidente ha ocurrido posiblemente en el mejor sitio para que pasara. Frente a la costa de Cartagena,…

Un método disminuye la mortalidad previa en caso de trasplante hepático

Mantener a temperatura ambiente el hígado de un donante durante las horas previas al trasplante podría reducir en un 20% el número de muertes en las listas de espera, según un estudio internacional con participación española. En los últimos años y debido al aumento de las tasas de enfermedad hepática, el suministro de órganos trasplantables…

Relationship between Clinic and Ambulatory Blood-Pressure Measurements and Mortality

BACKGROUND Evidence for the influence of ambulatory blood pressure on prognosis derives mainly from population-based studies and a few relatively small clinical investigations. This study examined the associations of blood pressure measured in the clinic (clinic blood pressure) and 24-hour ambulatory blood pressure with all-cause and cardiovascular mortality in a large cohort of patients in…

 

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